Interestingly, Naive T-Cells can be further subdivided into “good cops” and “bad cops” as in Lethal Weapon. The good ones, present in younger, healthier individuals, are naive and ready to go, like Bat-guano crazy Mel Gibson’s Martin Riggs character. The bad ones are like Danny Glover’s character, Roger Murtaugh, hiking up their pants and counting the days to retirement while muttering “I’m too old for this $h!t”
So we suspected that chronic CMV infection ages us but we only conprehended that the immune system burns out fighting it. Until this paper, we didn’t realize that it also steals the healthy gene transciption factors that the host cell needs to stabilize its telomers. It’s a double whammy.
From the outset of his two year course of taking TA-65 at 4 capsules nightly, “Satoshi” (a pseudonym) began feeling healthy, his hair grew stronger, he began to dream vividly. His energy was through the roof and he never got the colds and flus that he used to. Even more interestingly, he grew about an inch in his inseam and his posture and scoliosis improved. All his life, he had felt like an old man, but now, he knew for the first time what if felt like to feel young.
Just yesterday, I was speaking with my patient who remarked that her 88 year old husband and she hadn’t gotten the usual colds for years since starting TA-65. If what we think about immune senescence being at the heart of aging, then it is encouraging that so many patients taking a telomerase activator report decreased severity and frequency of colds and flus.
This article describes exactly what I’ve been saying for the last 6 years. My book, “Telomere Timebombs: defusing the terror of aging” outlines this exact and obvious conclusion: maintaining stem cell telomere integrity will allow for longer and healthier lives.