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Momma stem keeps the good china for herself

As I explain in my book,
“TELOMERE TIMEBOMBS: Defusing the Terror of Aging”, stemness is defined by two traits.  One is IMMORTALITY conferred mainly by telomerase activity maintaining the length of shortening telomeres, and the other is ASYMMETRIC DIVISION.

That means the momma stem makes two copies, a perfect momma and a less-than-perfect, more differentiated daughter.  We have known those more differentiated daughters have different gene expression and phenotypes by their epigenetic switches.

But This article shows that the organelles are divided inequally, the mysterious all-important mitochondria, are not divided equally.  Only the mom gets the “good china” and the daughter gets the worse mitochondria.


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