After two years of TA-65 use, his median length is now 12,500 (from an estimated 9,400) with a very nice drop in critically-short telomeres to 4.5% (from a baseline of up to 20%). So if you believe what most research is showing regarding the connection between shorter telomeres and longevity, Mark has gained over 30 years of longevity in a time where he should have lost three years.