How telomere erosion leads to chromosomal mutation, which causes dysfunction and cell death (we hope)
Dying young but with perfect babies is sustainable and advantaged; dying old but with abnormal babies is an evolutionary dead end.
I was at an ideas festival filled with some bright and accomplished people and I found myself rebuked by what I would consider true ignorance at least three times.
Liz Parrish, founder of BioViva Sciences discusses the objective improvements in her biomarkers after taking gene therapy for telomerase and follastatin.
In my search for wisdom about aging, I maintain that the primary cause is telomere shortening. This does not mean that methylation, signaling with stem cell produced vesicles (like packages with a purpose) don’t play a secondary role.