In the second of three interviews with Bill Andrews at the 2016 AMMG, we discuss the Henrietta Lacks (or HeLa) cervical cancer cells commonly used in cell research. Dr. Andrews also discusses why telomere erosion is less a factor in mice aging.
In honor of 420 (marijuana legalization day is April 20th and hipster code for the drug is “420”) we cite an article experimenting on mice liver cancer.
They suggested that treatment with cannabinoids decreases TERT (telomerase) expression and therefore inhibits hepatic carcinoma.
I got an email from a celebrity who takes TA-65 yesterday. I can’t reveal the name but the concern was over an article about TA-65 and increased cancer risk in mice.
Although he didn’t likely say it, this quote is often attributed to Prime Minister Benjamin Disraeli. “There are lies, damned lies, and statistics.” Well in this case, it the statistics don’t even show what the article claims. In my blog, mentioned in my email reply, I explain why.
For those wanting a more in-depth understanding of how TA-65 might work, I refer to you an email conversation I had with a patient, who was concerned that a blog referenced a Blasco paper demonstrating a 50% increase in liver cancer in mice after taking TA-65.
In this first segment, Dr. Chang explains that we really don’t know what the normal human birth endowment of telomere length is and we then discuss why lab mice have abnormally long telomeres and are therefore not a good model to study our aging.