It is now clearer that extracellular vesicles (aka exosomes) they are the primary method of communication between stem cells the other cells of the body.
The reason that there is a link between telomeres and all diseases is both causative in the local organs and coincidental in your white blood cells.
My stem cell/telomere theory of aging and disease is a necessary and sufficient explanation for nearly every disease you can imagine
When I’m asked about experts’ opinions, I think of a Bob Dylan lyric: “Don’t follow leaders; watch the parkin’ meters.”
We have a long way to go before we can do more than identify and trust in the black box of stem cells