My stem cell/telomere theory of aging and disease is a necessary and sufficient explanation for nearly every disease you can imagine
This endless, incremental, reiterative, and staid method of advancing knowledge is challenged by what I call the “Ginsu Principle”. You could sell many distinct knives for cutting bread, aluminum cans, tomatoes and wood. And you can have different theories for how these knives cut those substances. Or you could just accept that a knife can cut a lot of things because it’s sharp. Our research into telomere biology violates the Ginsu Principle in a big way.