The fact that progeria-affected kids have undeniable biological aging despite young epigenetic and chronological ages implies that telomerpathies that drive them are still the most robust explanation for aging globally
I was at an ideas festival filled with some bright and accomplished people and I found myself rebuked by what I would consider true ignorance at least three times.
Today, I feel we should discuss a critically important topic: change blindness.
In order to function, we have to maintain a simulation of reality and when we are distracted, emotionally perturbed, or lazy, we do not perceive change.
Watch my fast-paced interview with Dr. Aubrey de Grey, Chief Science Officer of the SENS Research Foundation. SENS is the Strategies for Engineered Negligible Senescence.
In my search for wisdom about aging, I maintain that the primary cause is telomere shortening. This does not mean that methylation, signaling with stem cell produced vesicles (like packages with a purpose) don’t play a secondary role.