Dying young but with perfect babies is sustainable and advantaged; dying old but with abnormal babies is an evolutionary dead end.
A body is a machine in turn made up of trillions of cellular machines, all exhibiting decreasing genomic integrity and stability as we age. Here are some insights which help to explain aging as the result of increasing entropy
Sperm telomeres are supported by hyper-efficient telomerase activity and they are one of the only tissue types to get progressively LONGER telomeres with advancing age
As shown in the graphic, the ability to retrieve eggs is not that uncommon, even in the over 44 population, but the rates of pregnancy are just 5% and live birth only 2%, explaining why the practice is generally frowned upon in this cohort.
BRCA1 is no more a “cancer gene” than policemen are crime-inducers. They don’t cause cancer but if they aren’t policing the DNA, cancers will develop.