Gene Therapy CEO and “patient zero” says her telomere length went from 6,710 DNA base pairs to 7,330 base pair in just six months.
I would guess that his telomere length would have been LONGER three years ago because there would have been many stem cells in crisis with lengthening but damaged chromosomes. But I believe his percentage of critically-shortened telomeres would have been higher (typically in the teens)
telomere shortening was rapid in the blood cells leading up until a few years before cancer diagnosis. In those years before diagnosis, the telomere lengths appeared to stabilize.
After two years of TA-65 use, his median length is now 12,500 (from an estimated 9,400) with a very nice drop in critically-short telomeres to 4.5% (from a baseline of up to 20%). So if you believe what most research is showing regarding the connection between shorter telomeres and longevity, Mark has gained over 30 years of longevity in a time where he should have lost three years.
In long-time users of telomerase activators, I tend to see a narrowing of the histogram which is great news as long as the progenitors are numerous and healthy. This means are less “crew cut” and “dreadlock” telomeres and that the system is rebalancing and lengthening the telomere efficiently.