Over time, the dutiful and dysfunctional stem cells die off but others, like the Mafia capos or career politicians, become unable to kill themselves so they persist and cause problems while still lengthening their telomres.
Watch my fast-paced interview with Dr. Aubrey de Grey, Chief Science Officer of the SENS Research Foundation. SENS is the Strategies for Engineered Negligible Senescence.
In my search for wisdom about aging, I maintain that the primary cause is telomere shortening. This does not mean that methylation, signaling with stem cell produced vesicles (like packages with a purpose) don’t play a secondary role.
I would like to recommend the TV show, Younger for its new take on telling women’s stories. Let’s hear it for the women who bravely face the challenges of balancing reproductive capacity, career, freedom, and having to tolerate men.
A body is a machine in turn made up of trillions of cellular machines, all exhibiting decreasing genomic integrity and stability as we age. Here are some insights which help to explain aging as the result of increasing entropy