You had one ‘perfect’ copy of DNA in your chromosomes when you were a single cell fertilized ege. Since then, each copy has made successive generations progressively worse
CRISPR-Cas is not like a human finding cutting and splicing an old fashioned movie reel…it depends on bacterial-derived micro-machines with an inherent error rate.
Our body doesn’t go in for a total flush so it is sort of like have the oil continuously exchanged as it becomes sludgy from the accumulation of damaged stem cells that results from replicative senescence.
So I guess I’ll just have to sit here like Leif Ericson in New England until other Columbi (plural of Columbus?) decide to plant their flag on this wonderful new world of common sense and scientifically-backed conclusions.
…we exist only because long ago, little bacteria, the mitochondria, were given a nice place to live inside our cells.