For today’s #WebinarWednesday, we return to the penultimate iHealthTube video interview that I did at the 2013 American Academy of Anti-Aging Medicine. I explain why we are like cars and that with time, if we survive all our cancers, we would eventually accumulate them all. Just like if you drive a car for millions of miles, you will replace all parts.
My belief is that replicative senescence, or the shortening of telomeres, can account for most cancers. Family history is indicated in very few cases and for the most part, they involve failure of DNA repair or cell suicide pathways. A landmark study in the Journal of the AMA suggests that indeed, all cancers are related to telomere shortening in a dose-dependen fashion: http://www.ncbi.nlm.nih.gov/pubmed/20606151