In honor of 420 (marijuana legalization day is April 20th and hipster code for the drug is “420”) we cite an article experimenting on mice liver cancer.
They suggested that treatment with cannabinoids decreases TERT (telomerase) expression and therefore inhibits hepatic carcinoma.
Here is the last PODCAST Number 45, which was about constipation.
Why do dogs eat that stuff? Why does it smell? What’s a normal shape? Everything you never wanted to know about defecation and didn’t really give a you-know-what about to begin with.
Google alerts for “telomeres” posted this interesting study validating my idea that replicative senescence is at the heart of liver disease. They engineered mice to have poor telomere repair and then watched as the large cell liver histology typical in hepatitis and cirrhosis developed.
Check out this very brief interview about how telomerase activation can enhance the anti-aging benefits of sleep:
When data from the Copehnhagen City Heart Study was published in 2013, they concluded that shorter telomeres in leukocytes was not associated with increased cancer after adjusting for age but that it WAS associated with reduced survival from cancer http://jnci.oxfordjournals.org/content/105/7/459.long
In 2015, the same data looked at certain gene tendencies that promote telomere shortening and concluded that cancer survival was IMPROVED when shortening was enhanced in the telomeres.
Contradiction? Not so fast.
