Tag: progeria

Real patient experiences

Solved: the Chicken came AFTER the Egg

In my search for wisdom about aging, I maintain that the primary cause is telomere shortening. This does not mean that methylation, signaling with stem cell produced vesicles (like packages with a purpose) don’t play a secondary role.

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Premature aging linked to telomeres – cure found

they could “cure” their HGPS mouse model by two two things. In figure C, they added telomerase activity. In figure D, they added a little extra LAP2α.

There are many who feel that telomeres and telomerase are not centrally related to aging. This study shows that for at least this classic model of premature aging, Sutton’ Law still applies.

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Aging genes and Oncogenes – what are they telling us?

So in a sense, good health is like keeping a bathtub full of clean water. The supply of water is nearly endless if we can keep the mesenchymal stem cell library frozen in our cartilage from aging when recruited. And if we can drain out the foul water (mutated stem cells), then we are going to be just fine.

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