Telomerase activators do not trump the natural pruning of length

Ed Park, MD aging, Biomarkers, dr ed park, Telomerase Activation Medicine, telomere measurement 4 Comments

Just a brief note about telomere length. I have noted that over the last nine years, taking telomerase activators in my patients can lead to increases but that this does not result in continuous lengthening. Instead, the overall health of the person appears maintained or improved but the measurable telomere length becomes stabilized.

We know from trees that live thousands of years that telomeres are not longer, they are just healthier (i.e. balanced without excessively long or short ends.)

A key finding of mechanism of this natural healthy pruning was described in this research paper out of Singapore describing the fourth known protein that binds to telomeres, called ZBTB48

This is very good news because instead of getting what might seem like the benefit of extremely long telomeres, we get sufficiently long telomeres to prevent mutation of our chromosomes. Thus, the long term use of telomerase activation confers genomic, cellular, and health benefits without circumventing the health maintenance of a manageable telomere length.

I am encouraged by this because if the telomeres just got longer and longer, it would create a gratuitous replicative burden, without benefit, and possibly beget unforeseen problems in cellular function. I say “without benefit” because as long as a telomere isn’t critically short, the chromosomes won’t mutate. Telomeres function like blank tape leader on old cassettes, protecting the music. You don’t need more that 6-10 seconds of silence before the music so creating cells with increasing minutes of blank tape leader would be pointless.

Interestingly, the protein discovered also influences mitochondrial localization so we see that as with the multiple, non-canonical roles of the telomerase enzyme, there is an intelligence and multipurpose roles of our critical enzymes responsible for preventing aging through genomic and mitochondrial dysfunction.

Ed Park, MD
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Ed Park, MD

I graduated from Harvard with honors in Biological Anthropology prior to earning my Medical Degree and Masters in Public Health from Columbia University.

In 2007, I became the nineteenth patient to sign up for the use of a herbally-extracted telomerase activator.

The results were so positive that I founded Recharge Biomedical Clinic in 2008 and have since become the leading medical expert in this exciting new field of regenerative medicine treating over 1,300 patients with this exciting new telomerase activation medicine.

I won two Houston Film Festival Awards for my screenplays about Hypatia of Alexandria and Ed Brown of Kentucky.

In 2010 I wrote and self-published a Sci-Fi Graphic Novel called MAXIMUM LIFESPAN

In 2013, I wrote and published "Telomere Timebombs; Defusing the Terror of Aging"

My websites are: (where you can learn about my RECHARGE adaptogenic supplement) and

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Ed Park, MD
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