A body is a machine in turn made up of trillions of cellular machines, all exhibiting decreasing genomic integrity and stability as we age. Here are some insights which help to explain aging as the result of increasing entropy
When we discuss the risk of telomere length to cancer risk, there are many studies but the conclusions we reach are limited by our simplistic assumptions.
In this 62-minute, we have a cheerful and accessible discussion that nonetheless goes quite deeply into my Telomere/Stem Cell Theory of Aging- right down a breakdown of Koch’s Postulates (the foundation of establishing disease causation versus correlation), the nature of stem cells, and how to naturally live longer and healthier
Instead of being thrown off the the trail by the differences, we should find the commonalities. Both models of aging- oxidative damage and telomere shortening cause chromosome disruption and bone marrow mesenchymal stem cell damage and depletion.
This week, the future became the present, as scientists published a study showing that an engineered molecule that facilitates cell death could reverse signs of aging in mice and hopefully cure aging