The fact that progeria-affected kids have undeniable biological aging despite young epigenetic and chronological ages implies that telomerpathies that drive them are still the most robust explanation for aging globally
What if the principle clock that truly matters is actually in the DNA of the cells of the hypothalamus?
A body is a machine in turn made up of trillions of cellular machines, all exhibiting decreasing genomic integrity and stability as we age. Here are some insights which help to explain aging as the result of increasing entropy
When we discuss the risk of telomere length to cancer risk, there are many studies but the conclusions we reach are limited by our simplistic assumptions.
In this 62-minute, we have a cheerful and accessible discussion that nonetheless goes quite deeply into my Telomere/Stem Cell Theory of Aging- right down a breakdown of Koch’s Postulates (the foundation of establishing disease causation versus correlation), the nature of stem cells, and how to naturally live longer and healthier