Over time, the dutiful and dysfunctional stem cells die off but others, like the Mafia capos or career politicians, become unable to kill themselves so they persist and cause problems while still lengthening their telomres.
A study out of Princeton looking at 1,567 9-yo children found that for each hour less than the recommended 9-11 hours of sleep, they averaged 1.5% shorter telomeres.
When we discuss the risk of telomere length to cancer risk, there are many studies but the conclusions we reach are limited by our simplistic assumptions.
In this 62-minute, we have a cheerful and accessible discussion that nonetheless goes quite deeply into my Telomere/Stem Cell Theory of Aging- right down a breakdown of Koch’s Postulates (the foundation of establishing disease causation versus correlation), the nature of stem cells, and how to naturally live longer and healthier
“flow-FISH was more accurate, reproducible, sensitive, and specific in the measurement of human leukocyte’s telomere length in comparison to qPCR”