In a recent study of 4,598 retired people, an association was found between childhood trauma and shorter telomeres.
As I like saying, you are never too old to get young and you are never too young to get old.
Studies have linked maternal stress to in utero with fetal telomere shortening.
Since some degree of telomere shortening may be needed for proper fetal development and the signal for labor onset, I wouldn’t recommend telomerase activation while pregnant.
Since we still don’t understand whether senescence plays a role in puberty onset, I probably would advise against extended telomerase activation in children.
But once you are in your 20s, I would say the 100% chance of stem cell telomere degradation versus the absence of any other major developmental milestones makes the benefits outweigh the risks. It is as though you are changing you oil every 3,000 miles instead of after 100,000 or after engine failure.
To understand how stress ages us prematurely at any age, watch this video I did on the subject: