General Disclaimer: This blog is for informational purposes only. It is not an advertisement for exosomes. The clinical use of exosomes has not been FDA-approved for prevention nor treatment of any disease condition and may carry unknown risks. Anecdotes provided do not constitute scientific proof and all patients were treated in the context of a fully informed consent and legally protected patient-physician relationship.
EXOSOMES 38: Bell’s (Facial Nerve) Palsy
This brief blog is a summary of an interesting case of Bell’s Palsy that improved after MSC exosome injection. I will discuss what Bell’s Palsy is and present the case.
The facial nerve controls movements and sensations to the face. In most cases, the cause of Bell’s Palsy is unknown and in most cases, it resolves. Some people are treated with steroids and antivirals although the response rate is low because not all injuries are due to inflammatory or viral causes. Common associations are pregnancy, diabetes, and a history of infections at the time of onset.
The lower face is controlled by both cerebral hemispheres whereas the lower face is only the same side. That is why a stroke often spares the upper face whereas Bell’s Palsy, which attacks the nerve, affects both upper and lower.
The results are an inability to control the eyelids smile symmetrically and often botox is used to paralyze opposing muscles to keep the eyes open. The patient often requires eyedrops to keep the eye moist. Rarely, taste may be affected, there is increased sensitivity to sound, and there can be drooling.
I had previously treated a woman with minimal improvement by injecting here facial nerve plexus. Nevertheless, ES, a 69-yo patient with a 12-year history of stable Bell’s Palsy after an emotional stress wanted to try. In addition to injecting 1B exosomes into the facial nerve plexus, we also injected painful trigger points on her trapezius, paraspinal muscles (for scoliosis), and performed a lumbar epidural injection at L4/L5 for back pain. She has an “S-shaped” double scoliosis (side curvature) that appears to be causing asymmetrical stresses.
Overnight, the patient reported improvement in back and shoulder pains. (N.B. We generally don’t charge more for multiple sites of injection despite the increased effort and risks.)
Amazingly, her facial nerve sensations and control improved after just 10 hours and has continued to improve. Here is a photo of before (4 mos ago) and ten days after the injection.
I think it is fairly clear that in her baseline state of the last twelve years, her right eyelid drooped and she struggled to have a symmetric smile. She believes that her condition improved overnight. Do you agree?
Here is a recording of Elane describing her results:
Of note, I had previously treated another similar patient who only experienced minimal improvement. I think the “heaviness” is interesting and I explain that in the “soft signs” blog 27
Another interesting point is that nerve damage from emotional stress was also the main factor in KH’s case which showed improvement in her tinnitus (see blog 36).
By way of disclosure, I just treated another patient with tinnitus after sound damage and his condition did not improve. That makes the response rate only one in three thus far. So 50% for Bell’s Palsy and 33% for Tinnitus? I don’t think it is that simple. It may have to do with what caused the dysfunction and how prepared the subject is to reverse the damage. Still, with additional unexpected benefits and a near zero chance of improvement with existing therapies, the use of exosomes might help selected people when administered within a monitored patient-physician relationship.
Injection of MSC exosomes is NOT FDA approved for treatment of Bell’s Palsy.
Archived exosome blogs….Please read them all at your convenience
I still have voluntary ASMR. Mom’s arthritis is greatly improved.
I explain why I believe exosomes aren’t inert. An amazing case of an overnight in heart rate variability is presented.
A case of whiplash and traumatic brain injury improved after exosome use.
After exosome injection, two runners were able to return to running after limitations from tendinosis that plagued them for months (in the case of the 60-yo man, and years (in the case of the 53-yo woman)
In this blog, I discussed how complicated clinical medicine can be. Different treatment protocols, ambiguous results ethical dilemmas and strange phenomena like acquired coffee aversion are part of what make treating with exosomes so challenging.
Using my left foot as an example, I attempt to explain that while some exosome effects are immediate, others take time. Remodeling of damaged tissues is a complicated process. My foot is still scarred and probably will be for life.
A patient after dental exosome injection becomes pain free after 4 years of suffering.
I explain why lab testing of freshly thawed exosomes is SUPPOSED to come back as normal saline.
A nine-part comprehensive explanation of exosomes.
I interviewed the principal scientists of Kimera Labs and other experienced clinicians using exosomes
66-yo Deb B went from not being able to do one squat to 100 per day after exosome injection.
80-yo Doug describes in his video how much his knees have improved since getting exosome injections. He is reaching new athletic peaks with no signs of stopping.
My 82-yo mom underwent microneedling with exosomes with fantastic results. Most impressive was the absence of “downtime” from redness or bruising.
54-yo weightlifter with chronic pain from a rotator cuff tear shows remarkable improvement in just four days! He re-injured it at the gym so had to undergo a repeat shoulder injection
48-yo woman with severe face blindness experiences some improvement after nasal injections of exosomes. Her ability to remember new faces has improved permanently
I delivered two lectures in Hawaii. The first was about exosomes generally and the second is a password-protected video about clinical applications.
Three cases of middle-aged women reporting enhanced enjoyment and renewed capacity to read after nasal exosome therapy
Two cases of improved dental health presented. We discuss the hazards of EMF and the promising future of dental regenerative therapy
We discuss the notion of energy centers known as chakras and the fact that we are electrical beings
A case of improvement in Seborrheoic Dermatitis after microneedling with MSC exosomes is presented.
I explain how poor we are at assessing change and how attribution and recall bias play important roles
In the past year, there has been a lot of shifting loyalties in the exosome space resulting in a lot of rumor, innuendo, and bad press. With various parties trying to get each other in trouble with federal regulators, it is a treacherous business to be in.
I describe a case of an 86-yo woman whose chronic leg rash disappeared after improvement in her leg circulation
I use a car wash analogy to answer the question “how long do exosomes last?” The answer is it depends on how dirty and damaged the car is, how well you clean it, and how dirty you get it after washing.
I describe four cases of improvement of osteoartritic knees from my trip to Hawaii.
I explain the three definitions of placebo and why I believe most of the effects of exosomes cannot be attributed to the so-called placebo effect.
Some remarkable “soft signs” of exosome effects include itching (new nerves), twitching (new muscles), and heaviness (a healing FORCE).
Three amigos came to see me and all enjoyed benefits. The best was the 48-yo gentleman who had a dramatic improvements to his irritable bowel syndrome, varicose veins, and appearance.
I address the common observation from patients that exosomes seem “smart” or that they know where to go. In fact, I doubt this is true and that they are no smarter than player piano scrolls are good musicians.
I gave a lecture at the University of Hawaii with about 80 attendees. Around 10 of them were actual patients. Hear in their own words how exosomes helped them.
I describe two cases of improved leg swelling and explain what causes this common condition and how exosomes may be improving it.
We present an amazing case of overnight nerve regeneration after ultrasound-targeted exosome injections.
A fascinating case of resumption of menstruation after taking IV exosomes
I speculate why a patient reported improvement in her double vision after exosome injection
My mom used to have cold hands and feet. Now she does not. I present a new technique for arterial and peri-arterial injection of exosomes
I review a case of tinnitus that improved after exosome use and explain the common condition
I reviewed 89 patients and 144 encounters in 256 sites. Overall, very good response rates and safety.