For our 39th blog, I want to talk about delayed reactions. This blog was initiated be a phone call from one of the patients who recognized their initials on the 37th blog about my first year’s results. He felt bad that he left me with the impression that his knees were no better. In fact, they were much better! You can listen to our call here:
Interestingly, three of the ten patients who were on the “no response” list should be taken off making the adjusted response rate of 92%. I spoke with SR and he said there was some improvement and VC improved after several months (which he attributed to a steroid injection, although those effects tend to be fleeting and not regenerative).
I confess that with some cases (often nerves) improving overnight as in blogs 7, 32, and 38, I have gotten used to a rapid time course. In most patients, the effects are felt within the first two weeks if not sooner…so why did Sam not achieve pain relief until six months?
Perhaps the remodeling and regeneration is delayed in older patients because the epigenetic gene silencing makes the cells resistant to the message? Perhaps there needs to be recruitment of outside stem cells that takes time? Perhaps the remodeling is a process, not a quick fix…like making a butterfly from a caterpillar egg.
No news was good news for Vince
Vince is a very athletic 57yo actor who had shoulder, knee, and wrist injections in November of 2019. Initially, his knees were better and because I didn’t warn him sufficiently, he may have overdone it playing volleyball; nevertheless, they are still better than they were. I didn’t hear anything good about the shoulders but I did know the knees were still troublesome. Little did I know they completely recovered and no longer bother him at all.
Regrowing a backbone
Another great example of a case that took a while to recover is Thalya who suffered a crushed verterbra June 2019 and was treated with lumbar epidural exosomes in November, 2019. The cruching persisted for months after the treatment but eventually, it subsided. When asked about the crunching in late August, 2020, she wrote:
"The healing process is still unfolding"
Here is another patient, Mary Jo, age 66, who fell from a horse 24 years ago and had severe hip damage and nerve impingement since. She wrote one of the most eloquent descriptions of her recovery that reminded me of my blog on the “soft signs” of exosome healing. Perhaps, as she suggests, some cases are just a lot more complicated with layers of accumulated damage that need to be addressed:
If you are a patient and you have new improvements or even setbacks to report, please email me back so I can continue to learn. If you would like to refer someone or find out how I can help you, please reach out by email.
Archived exosome blogs….Please read them all at your convenience
I still have voluntary ASMR. Mom’s arthritis is greatly improved.
I explain why I believe exosomes aren’t inert. An amazing case of an overnight in heart rate variability is presented.
A case of whiplash and traumatic brain injury improved after exosome use.
After exosome injection, two runners were able to return to running after limitations from tendinosis that plagued them for months (in the case of the 60-yo man, and years (in the case of the 53-yo woman)
In this blog, I discussed how complicated clinical medicine can be. Different treatment protocols, ambiguous results ethical dilemmas and strange phenomena like acquired coffee aversion are part of what make treating with exosomes so challenging.
Using my left foot as an example, I attempt to explain that while some exosome effects are immediate, others take time. Remodeling of damaged tissues is a complicated process. My foot is still scarred and probably will be for life.
A patient after dental exosome injection becomes pain free after 4 years of suffering.
I explain why lab testing of freshly thawed exosomes is SUPPOSED to come back as normal saline.
A nine-part comprehensive explanation of exosomes.
I interviewed the principal scientists of Kimera Labs and other experienced clinicians using exosomes
66-yo Deb B went from not being able to do one squat to 100 per day after exosome injection.
80-yo Doug describes in his video how much his knees have improved since getting exosome injections. He is reaching new athletic peaks with no signs of stopping.
My 82-yo mom underwent microneedling with exosomes with fantastic results. Most impressive was the absence of “downtime” from redness or bruising.
54-yo weightlifter with chronic pain from a rotator cuff tear shows remarkable improvement in just four days! He re-injured it at the gym so had to undergo a repeat shoulder injection
48-yo woman with severe face blindness experiences some improvement after nasal injections of exosomes. Her ability to remember new faces has improved permanently
I delivered two lectures in Hawaii. The first was about exosomes generally and the second is a password-protected video about clinical applications.
Three cases of middle-aged women reporting enhanced enjoyment and renewed capacity to read after nasal exosome therapy
Two cases of improved dental health presented. We discuss the hazards of EMF and the promising future of dental regenerative therapy
We discuss the notion of energy centers known as chakras and the fact that we are electrical beings
A case of improvement in Seborrheoic Dermatitis after microneedling with MSC exosomes is presented.
I explain how poor we are at assessing change and how attribution and recall bias play important roles
In the past year, there has been a lot of shifting loyalties in the exosome space resulting in a lot of rumor, innuendo, and bad press. With various parties trying to get each other in trouble with federal regulators, it is a treacherous business to be in.
I describe a case of an 86-yo woman whose chronic leg rash disappeared after improvement in her leg circulation
I use a car wash analogy to answer the question “how long do exosomes last?” The answer is it depends on how dirty and damaged the car is, how well you clean it, and how dirty you get it after washing.
I describe four cases of improvement of osteoartritic knees from my trip to Hawaii.
I explain the three definitions of placebo and why I believe most of the effects of exosomes cannot be attributed to the so-called placebo effect.
Some remarkable “soft signs” of exosome effects include itching (new nerves), twitching (new muscles), and heaviness (a healing FORCE).
Three amigos came to see me and all enjoyed benefits. The best was the 48-yo gentleman who had a dramatic improvements to his irritable bowel syndrome, varicose veins, and appearance.
I address the common observation from patients that exosomes seem “smart” or that they know where to go. In fact, I doubt this is true and that they are no smarter than player piano scrolls are good musicians.
I gave a lecture at the University of Hawaii with about 80 attendees. Around 10 of them were actual patients. Hear in their own words how exosomes helped them.
I describe two cases of improved leg swelling and explain what causes this common condition and how exosomes may be improving it.
We present an amazing case of overnight nerve regeneration after ultrasound-targeted exosome injections.
A fascinating case of resumption of menstruation after taking IV exosomes
I speculate why a patient reported improvement in her double vision after exosome injection
My mom used to have cold hands and feet. Now she does not. I present a new technique for arterial and peri-arterial injection of exosomes
I review a case of tinnitus that improved after exosome use and explain the common condition
I reviewed 89 patients and 144 encounters in 256 sites. Overall, very good response rates and safety.
I present the case of a 69yo woman with a 12-yr history of Bell’s Palsy that improved overnight